Background Although adoptive transfer of CD19-directed chimeric antigen receptor (CAR) T-cells (CD19-CAR T-cells) achieves high rates of complete response in patients with B-cell acute lymphoblastic leukemia (B-ALL), relapse is common.Bone marrow (BM) mesenchymal stem/stromal cells (BM-MSC) are key components of the hematopoietic niche and are impl

Abstract Background This study documents cycad-human relationships in Mexico, Belize, Guatemala, El Salvador, and Honduras over the last 6000 years.The impetus was acute need for a better understanding of previously undocumented uses of cycads in this region, and the need to improve cycad conservation strategies using ethnobotanical data.We hypothe

Introduction: Freshly isolated uncultured adipose tissue-derived stromal cells (u-ADSCs), containing miscellaneous cells like the relatively abundant mesenchymal stem cells, are attractive for repair and regenerative therapy.However, the detailed characteristics and therapeutic efficacy of u-ADSCs Wash-in Waterproofer obtained from disease-affected

The main focus of this research is to examine the legal protection of simple patent innovations within the Indonesian patent system, considering their substance, structure, and legal culture.The objective is to advocate for the reformulation of regulations concerning the social and economic utilization of intellectual property, specifically simple

Solitary bees pollinate wild plants and crops.In the temperate zone, they mainly pollinate fruit trees.Most species nest in the soil, but mason bees nest in wooden cavities above ground.Their presence in orchards can be augmented by provision of artificial nesting sites.Two species of mason bees frequently use these artificial nesting opportunities